Table 3.
Experimental values for the response variable
| Charateristics | The smallest PF-NPs |
|---|---|
| Optimum conditions | |
| Polyglutamic acid (mg/mL) | 1.332 |
| Fucoidan (mg/mL) | 0.014 |
| Observed values | |
| Particle size (nm) | 286.7 ± 36.6 |
| Zeta potential (mV) | −21.5 ± 1.0 |
| Polydispersity index | 0.147 ± 0.019 |
| Derived count rate (kcps) | 231,144 ± 10,847 |
| Encapsulation efficiency (%) | 20.78 ± 0.20 |
| Ginsenoside release in SGF1 (%) | 31.47 ± 6.17 |
| Ginsenoside release in SIF2 (%) | 67.57 ± 9.81 |
SGF, simulated gastric fluid; SIF, simulated intestinal fluid.
1)
Exposure of the PF-NPs to simulated gastric fluid (pH 1.2) for 2 h.
2)
Exposure of the PF-NPs to simulated intestinal fluid (pH 6.8) for 6 h.