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. 2021 Mar 26;21(5):416. doi: 10.3892/ol.2021.12677

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Copyright: © Ren et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Knockdown of circCCDC66 inhibited thyroid cancer cell proliferation. (A,C) Following si-circCCDC66#1 was transfected into CAL62 and TPC1 cells, circCCDC66 expression was significantly decreased, which was not the case with si-circCCDC66#2. (B and D) Results from Cell Counting Kit-8 showed that the proliferation of CAL62 and TPC1 cells was significantly decreased following circCCDC66 silencing by si-circCCDC66#1, which was not the case with si-circCCDC66#2. **P<0.01. NC, negative control; OCD, optical density; si, silencing.