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. 2021 Mar 26;21(5):416. doi: 10.3892/ol.2021.12677

Figure 4.

Figure 4.

Knockdown of circCCDC66 inhibited TC cell invasive ability in vitro. (A and C) Number of nuclei decreased significantly after circCCDC66 silencing both in CAL62 and TPC1 cells. (B and D) Relative invasive ability of CAL62 and TPC1 cells following circCCDC66 knockdown was 3/4 lower than the control group. **P<0.01. NC, negative control; si, silencing.