Photomicrograph of liver tissue (H & E; 100x).
Representative image of each group
(A) Control mice showing normal hepatic chord, hepatocytes, central canal and kupffer cells; (B) SM-4LD50 arrow showing severe necrosis, arrowheads showing ballooning of hepatocytes and distortion of lobular pattern; (C) NAC-50 arrow showing reduction of severity of lesions as compared to B; (D) DRDE07−25 arrow showed slight decrease in severity of degenerative changes than B; (E) DRDE07−50; (F) NAC-25+DRDE07−25 arrow showing minimal degenerative changes as compared to B; (G) NAC-50+DRDE07−50; (H) NAC-100+DRDE07−50