Fig. 3.
Photomicrograph of spleen tissue (H & E;100x).
Representative image of each group
(A) Control mice spleen showing normal spleenic histology with germinal center, red pulp and marginal zone of white pulp; (B) SM-4LD50 arrow showing severe necrosis/apoptosis; (C) NAC-50 arrow showing fibrinous exudates and arrowheads showing necrosis/apoptosis; (D) DRDE07−25; (E) DRDE07−50 arrow showing fibrinous exudates and arrowheads showing necrosis/apoptosis; (F) NAC-25+DRDE07−25 showing lymphoid depletion; (G) NAC-50+DRDE07−50 arrow showing fibrinous and arrowheads showing lymphoid depletion ; (H) NAC-100+DRDE07−50