Table 1.
Baseline characteristics of the variables included in the training and validation data sets
| Features | Training set (n = 5828) | Validation set (n = 3383) |
|---|---|---|
| Patient composition | ||
| SET | 5264 | 3082 |
| DET | 564 | 301 |
| Age*, y | 30.46 ± 4.20 | 30.70 ± 3.94 |
| Attempt times of IVF* | 0.95 ± 0.43 | 0.78 ± 0.54 |
| Antral follicle count* | 13.64 ± 6.13 | 13.37 ± 6.36 |
| Follicle stimulating hormone*, IU/L | 7.59 ± 2.35 | 7.68 ± 2.79 |
| Luteinizing hormone*, IU/L | 4.71 ± 3.26 | 4.95 ± 6.08 |
| E2 per mature oocyte, pmol/L | 309.60 ± 141.26 | 265.68 ± 133.16 |
| E2 on HCG day*, pmol/L | 2810.88 ± 1424.43 | 2174.64 ± 1046.56 |
| Endometrial Thickness*, mm | 11.79 ± 2.40 | 11.98 ± 2.55 |
| MetaphaseII(M II)* | 9.86 ± 4.14 | 9.25 ± 4.02 |
| 2pronucleus(PN)* | 6.79 ± 3.35 | 6.31 ± 3.22 |
| Oocyte Numbera* | 11.03 ± 4.45 | 10.64 ± 4.49 |
| 2PN/MII* | 0.70 ± 0.19 | 0.69 ± 0.20 |
| Frozen Sperm | 6.0% | 6.3% |
| Male Factorb | ||
| Oligospermia | 9.2% | 10.3% |
| Asthenospermia | 12.8% | 20.0% |
| Azoospermia | 7.1% | 9.1% |
| Female Factorb | ||
| Endometriosis | 3.0% | 4.4% |
| Ovulation Disorder | 5.9% | 7.8% |
| Unknown | 5.2% | 12.3% |
| Sperm Retrieval | ||
| Ejaculation | 95.2% | 95.2% |
| MESA | 0.3% | 0.7% |
| TESA | 1.0% | 1.3% |
| PESA | 3.5% | 2.8% |
| Stimulation Protocolb | ||
| Agonist Protocol* | 71.4% | 70.8% |
| Antagonist Protocol | 22.8% | 28.5% |
| Endometrial Typeb | ||
| A* | 83.3% | 85.0% |
| B | 2.0% | 0.4% |
| C* | 21.4% | 19.7% |
| Infertilityc | ||
| Primary | 64.9% | 70.4% |
| Secondary* | 35.1% | 29.6% |
| Fertilization Methodb | ||
| IVF | 72.5% | 57.9% |
| ICSI* | 24.5% | 34.8% |
| Embryo Features | ||
| Number of Blastomere* | 7.93 ± 0.89 | 8.06 ± 0.93 |
| Fragmentd* | 0.37 ± 0.50 | 0.32 ± 0.48 |
| Equalitye* | 0.91 ± 0.95 | 0.87 ± 0.91 |
*The selected features after performing feature selection are marked by asterisks
SET single-embryo transfer, DET double-embryo transfer, IVF in vitro fertilization, ICSI intracytoplasmic sperm injection, E2 estradiol, hCG human chorionic gonadotropin, MESA microscopic epididymal sperm aspiration, TESA testicular sperm aspiration, PESA percutaneous epididymal sperm aspiration
aNumber of oocytes retrieved; b for multi-category features, the sum of the proportion for each category may not equal 100% because the missing value exists or another small proportion of category features is not included; c infertility is encoded by 0 or 1 if the patient is primary or secondary, respectively; d the fragment is encoded by three values: 1 to 3 representing no fragment, 5–15% fragment, and > 15% fragment, respectively; e the equality is encoded by five values, 0 to 4, and represent equal, sort of equal, unequal, sort very unequal, and very unequal, respectively.