Figure 1.

Experimental details. (A) Timeline for individual animal treatments. Rapamycin was given daily by oral administration to all animals, and blood and tissue sampling were performed as indicated. (B) Animal sex, age, weight, injection details, and levels of pre-existing anti-AAV6 antibodies at study initiation. Animals IDs from Supplementary Fig. S6 were changed for clarity to reflect the control PBS-injected (C1), intravenously injected (IV1), and subcutaneously injected (SC1-SC3) animals. IV, intravenous; NA, not applicable; PBS, phosphate-buffered saline; SC, subcutaneous; vg, vector genomes.