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. 2021 Mar 22;118(13):e2019276118. doi: 10.1073/pnas.2019276118

Fig. 6.

Fig. 6.

Sequence conservation at RDR2 and NRPD1 interaction sites. (A) Alignment of A. thaliana RNA-dependent RNA polymerases RDR1 through RDR6 and N. crassa QDE-1, in the region that includes the conserved active site aspartates (*) and Pol IV (NRPD1) interaction site. Identical amino acids are highlighted in green; similar amino acids are highlighted in yellow. The cysteines of the putative zinc coordination sites in RDR2 interactions sites 1 and 2 are denoted by (#). (B) Sequence conservation at the Pol IV (NRPD1) interaction site among RDR2 orthologs of A. thaliana, maize (Zea mays), rice (Oryza sativa), soybean (Glycine max), cycad (Cycas revoluta) and pine (Pinus canariensis). (C) Sequence conservation at the RDR2-interaction sites of NRPD1 orthologs of maize, rice, soybean, cycad, and pine.