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. 2021 Mar 22;118(13):e2025197118. doi: 10.1073/pnas.2025197118

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Fig. 3. — No PPARγ requirement for accumulation of the putative tissue-Treg precursor population. (A) Frequencies of KLRG1⁺ and ST2⁺ cells among PPARγ⁻ and PPARγ^lo splenic Tregs of 6- to 8-wk-old Pparg-Tdt.Foxp3-Gfp mice. (A, Left) Representative dot plots. (A, Right) Summary plots. Mean ± SD; unpaired two-tailed t test; ****P < 0.0001. (B–D) Frequencies of Tregs among CD4⁺ T cells (B), KLRG1⁺ cells among Tregs (C), and ST2⁺ cells among Tregs (D) from spleens of 6- to 8-wk-old Pparg^+/+.Foxp3-Cre or Pparg^f/f.Foxp3-Cre mice.