Fig. 6.
Adoptive-transfer studies. PPARγlo Tregs from spleen and lymph nodes of 6- to 8-wk-old CD45.1−2+ Pparg-Tdt.Foxp3-Gfp mice were sorted and transferred into 10-wk-old CD45.1+2+ Foxp3-Dtr recipients treated with DT before, on, and after the day of transfer. i.v., intravenously; LN, lymph nodes; w, week. (A) Experimental schema. (B) Representative dot plot showing frequencies of donor-derived cells among Tregs in the indicated organs. Values refer to the fraction of Tregs in the adjacent gate. (C) Summary plot. Mean ± SD. Representative of two independent experiments.