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. Author manuscript; available in PMC: 2021 Apr 5.
Published in final edited form as: Crit Rev Biomed Eng. 2020;48(1):29–62. doi: 10.1615/CritRevBiomedEng.2020033151

TABLE 2:

Solid state nanopore materials

Solid state Material Thickness range
(nm)
Pore diameter
(nm)
Ideal biomarker/
polymer class
(See reference (9) for image) Silicon 18.0–75.0 > 5.0 dsDNA, dsRNA, protein, peptide, antibody capture, synthetic polyelectrolyte
graphic file with name nihms-1680373-t0029.jpg Gaphene 1.0–5.0 > 2.0 dsDNA, ssDNA, dsRNA, ssRNA, protein, peptide, antibody capture, synthetic polyelectrolyte
graphic file with name nihms-1680373-t0030.jpg Aluminum 5 × 104 to 10 × 104 > 10.0 dsDNA, dsRNA, protein, peptide, antibody capture
graphic file with name nihms-1680373-t0031.jpg Boron nitride 1.0–1.3 > 12.3 dsDNA, dsRNA, protein, peptide, antibody capture
graphic file with name nihms-1680373-t0032.jpg Molybdeneum disulfide 6.5 > 5.0 dsDNA, ssDNA, dsRNA, ssRNA, protein, peptide, antibody capture, synthetic polyelectrolyte
graphic file with name nihms-1680373-t0033.jpg Hafnium oxide 2.0–7.0 > 1.4 dsDNA, ssDNA, dsRNA, ssRNA, protein, peptide, antibody capture, synthetic polyelectrolyte
graphic file with name nihms-1680373-t0034.jpg Glass (Borosilicate) 20.0–75.0 > 14.0 dsDNA, dsRNA, protein, peptide, antibody capture
graphic file with name nihms-1680373-t0035.jpg Lipid coated Depends on membrane material Depends on membrane material Depends on membrane material