Extended Data Fig. 4 |. Cryo-EM data processing for GABAB/SKF97541/GS39783.
a, Single particle cryo-EM data processing scheme using cryoSPARC. b, Micrograph showing picked particles. c, Representative 2D class averages show distinct secondary structure features. d, Particle angular distribution of the final cryo-EM reconstruction. e, Structural model shown in cartoon representation and colored by the B-factors. f, Density map colored by local resolution showing higher resolution at the interface between GB1 and GB2. g, The heterodimer interface includes both LB1 and LB2 lobes, as well as TM6 with a total interface area of 1930 Å2. Residues involved in dimerization contacts are colored in purple.