Fig. 5.

Ability of the Bayesian approach to estimate pharmacokinetic parameters when doses of a drug conforming to a one-compartment model with nonlinear elimination as described in Fig. 3. Significant correlations between the true patient values and the Bayesian estimates are shown. The ka and k_m were not significant. The half-life shown is the expected value when a dose is given that is well below the k_m of the drug (calculated as . Data construction and sampling are as described in Fig. 3.