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. 2020 Nov 27;15(6):602–611. doi: 10.4103/1735-5362.301345

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Copyright: © 2020 Research in Pharmaceutical Sciences

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Fig. 1 — Effects of AT (group E1) on (A) average speed (mm/sec), (B) beam walking time, and (C) line crossing frequency in open field test and in CPZ-withdrawn rats compared to sham-treated control (group C) and PBS treatment (group E2). Values are mean ± SEM; n = 8. *P < 0.05 Indicates significant difference compared to group C and ^#P < 0.05 vs group E2. Weeks 1-5: CPZ treatment (groups E2 and E1); Weeks 6 and 7: AT treatment (E2) and PBS treatment (E1). CPZ, Cuprizone; AT, Alpha-tocopherol, Ws, weeks.