Cumulative absolute risk and 10-year absolute risks of pancreatic cancer estimated using simulated data of 20,000 men and 20,000 women with smoking status and family history status based on the average of imputed datasets. Each color line represents different relative risk percentiles in each gender group and the percentiles were estimated based on the clinical/genetic/biomarker model (including BMI, waist-to-hip ratio, physical activity, diagnosed diabetes, wGRS, proinsulin, adiponectin, interleukin-6, and total BCAAs). (A) Men in the full follow-up population, (B) women in in the full follow-up population, (C) men in the 0–10 years follow-up population, and (D) women in the 0–10 years follow-up population.