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. Author manuscript; available in PMC: 2021 Apr 5.
Published in final edited form as: Clin Cancer Res. 2019 Apr 19;25(14):4264–4270. doi: 10.1158/1078-0432.CCR-19-0361

Table 3.

Rates of Selected Grade 3/4 Adverse Events

Total Cohort n=297 Number with available data
Total TLS 8.1% 296
Neutropenia,1 % 39.6% 189
Thrombocytopenia,2 % 29.2% 188
Febrile neutropenia, % 7.9% 188
Infections, % 25% 189
Diarrhea,3 % 6.9% 186
1.

Neutropenia defined as absolute neutrophil count < 1000/μL

2.

Thrombocytopenia defined as platelet count < 50,000/μL

3.

Diarrhea defined as > 7 stools per day