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. 2021 Apr 5;16(4):e0248471. doi: 10.1371/journal.pone.0248471

Table 2. Preferred switch when no inertia occurs (a) towards treatment class and (b) towards treatment type.

a. Preferred switch towards angiotensine converting enzyme inhibitors and beta-blockers
Preferred strategy treatment class
N After switch
BB CCB ACEi ARB Thiazides-type Thiazide-like Other Diuretics
Before switch BB 807 90% 19% 89% 5% 8% 9% 2%
CCB 459 40% 72% 85% 11% 8% 27% 3%
ACEi 773 53% 42% 97% 2% 3% 26% 2%
ARB 188 53% 44% 45% 54% 36% 13% 4%
Thiazides-type 183 70% 35% 78% 16% 28% 20% 1%
Thiazide-like 122 36% 54% 93% 5% 4% 68% 2%
Diuretics other 57 63% 25% 81% 7% 5% 23% 37%

Abbreviations: BB: beta-blocker; CCB: calcium channel blocker; ACEI: angiotensine converting enzyme inhibitor; ARB: angiotensin receptor blockers; SPC: single pill combination. SPC only = exclusive use of SPCs / SPC Plus = use of SPCs and single molecule antihypertensive drugs.