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Shown are the main steps involved in this study for image preparation, MRI and histology alignment, and myelin and cellularity estimation using MRI. Note: RGB: red, green, blue; Myelin/cellularity GT: myelin and cellularity value ground truth; GMM: Gaussian mixture model; Segmentation GT: segmentation ground truth of histology; GMRF: Gaussian Markov random field; Seg. reg: segmentation regression; GAM: generalized additive model.
