Table 3. Radiosensitivity parameters.
Cells | D0 | Dq | N | SF2 | SER |
---|---|---|---|---|---|
H1299R | 3.018412 | 0.1690311 | 1.056 | 0.501294312±0.168487766* | 1 |
H1299R-shRNA-NC | 2.97619 | -0.3464286 | 0.8836 | 0.476918775±0.0075201010 | 1.014186594 |
H1299R-shRNA-miR183 | 2.255809 | -0.8996165 | 0.6012 | 0.271951284±0.0101135099* | 1.338061866 |
H1299 | 2.747252747 | -1.189285714 | 0.5671 | 0.309003681±0.0309269512 | 1 |
H1299-EGFP-NC | 2.760143527 | -1.337013525 | 0.5156 | 0.301589242±0.168818422 | 0.99532967 |
H1299-EGFP-miR183 | 2.801905296 | -0.16391146 | 0.9415 | 0.474246149±0.0266155100* | 0.980494505 |
H1299R-shRNA-NC vs H1299R-shRNA-miR183,*P<0.05, n=3; H1299-EGFP-NC vs H1299-EGFP-miR183, *P<0.05, n=3; H1299 vs H1299R *P<0.05, n=3. D0: mean lethal dose; Dq: quasi-threshold dose, which is the intersection of straight line portion of the curve and dose axis intersecting the 100% survival level, the size of the shoulder area, and the smaller value represents the sub-lethal repair ability; N: the number of extrapolation, which is the focal point that intersects the survival axis by straight line portion of the curve, and reflects the number of radiosensitive areas contained in the cells; SF2: surviving fraction at 2Gy; SER: sensitization enhancement ratio.