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. 2021 Apr 6;143(14):1426–1449. doi: 10.1161/CIRCULATIONAHA.120.049254

Figure 1.

Figure 1.

Formation, characterization, and secretion of various extracellular vesicles such as microvesicles, exosomes, and apoptosomes. Blue indicates extracellular compartment; red indicates intracellular compartment; and yellow indicates acidic compartment. Note that organelle proportions are not to scale. EV indicates extracellular vesicles; ILV, intraluminal vesicles; L, lysosome; MVB, multivesicular bodies; PM, plasma membrane; RER, rough endoplasmic reticulum; and TGN, trans-Golgi network.