Table 2.
Drug-likeliness analysis results of 10 phytochemicals targeting Furin
| Compound/Pubchem CompoundCID | Source | Properties | ||||
|---|---|---|---|---|---|---|
| Molecular weight (< 500 Da) | Logp (< 5) | H-Bond donor (< 5) | H-bond acceptor (< 10) | Violations | ||
| Resveratrol/445,154 | Polygonum cuspidatum(common knotweed) | 228.24 | 2.26 | 3 | 3 | 0 |
| Psoralidin/5,281,806 | Psoralea corylifolia (babchi) | 336.34 | 2.88 | 2 | 5 | 0 |
| Harmine/5,280,953 | Peganum harmala (harmal) | 212.25 | 1.56 | 1 | 2 | 0 |
| Boswellic acid/168,928 | Boswellia serrata(Indian frankincense) | 456.70 | 5.82 | 3 | 2 | 1 |
| Damnacanthal/2948 | Morinda citrifolia (Indian mulberry) | 282.25 | 0.27 | 1 | 5 | 0 |