Table 4.
Drug-likeliness analysis results of 10 phytochemicals targeting RdRp
| Compound/Pubchem CompoundCID | Source | Properties | ||||
|---|---|---|---|---|---|---|
| Molecular weight (< 500 Da) | Logp (< 5) | H-Bond donor (< 5) | H-bond acceptor (< 10) | Violations | ||
| Curcumin/969,516 | Curcuma longa (turmeric) | 368.38 | 1.47 | 2 | 6 | 0 |
| Ladanein/3,084,066 | Marrubium peregrinum(horehound) | 314.29 | 0.47 | 2 | 6 | 0 |
| Fisetinidol/442,397 | Bauhinia pentandra(mountain ebony) | 274.27 | 0.79 | 4 | 5 | 0 |
| Epiafzelechin/443,639 | Actinidia chinensis(Kiwi fruit) | 274.27 | 0.79 | 4 | 5 | 0 |
| Vitex norditerpenoid 1/ 11,208,535 | Vitex trifolia (nichinda) | 290.44 | 3.59 | 0 | 2 | 0 |