Table 3.
Univariate and multivariate Cox proportional hazards models for mortality in patients with MDS.
| Univariate analysis | Multivariate analysis | |||
| HR (95%CI) | P | HR (95%CI) | P | |
| Age | 1.00 (0.97–1.04) | .83 | – | – |
| Gender; female vs male | 0.32 (0.07–1.47) | .14 | – | – |
| Karyotype | – | – | ||
| Intermediate vs good | 6.82 (1.37–34.04) | .02 | – | – |
| Poor vs good | 11.69 (2.23–61.32) | <.01 | – | – |
| Cytopenia; 2/3 vs 0/1 lineage | 1.00 (0.33–2.98) | 1.00 | – | – |
| Bone marrow blasts (%) | 0.95 (0.73–1.24) | .70 | – | – |
| IPSS score; ≥1.5 vs <1.5 | 3.25 (1.05–10.08) | .04 | 4.79 (1.40–16.34) | .01 |
| With AIMs vs without AIMs | 3.24 (1.03–10.23) | .045 | 4.76 (1.39–16.35) | .01 |
AIMs = autoimmune manifestations, CI = confidence interval, HR = hazard ratio, IPSS = International Prognostic Scoring System.