Table 2.

Side effects of CIK/DC-CIK treatment and myelosuppression.

					Gastrointestinal adverse reaction		Myelosuppression
Study and year	Fever	Chills	Rash	Headache	Chemo/CIT	Control	Chemo/CIT	Control
Chang et al 2013	–	–	–	–	48.5%	54.5%	24.2%	39.4%
Shu et al 2015	74.6%	–	–	Mild	–	–	–	–
Wen et al 2015	–	–	–	–	82.9%	80%	78%	80%
Xi et al 2015	11.5%	–	–	–	–	–	–	–
Yan et al 2015	8.8%	Mild	–	–	55.9%	73.5%	11.8%	44.1%
Zhao et al 2015	64%	20%	10%	–	62%	88%	52%	74%
Zhang et al 2016	65.6%	3.1%	–	–	Mild	Mild	1–2 degree	1–2 degree

CIK = cytokine-induced killer cell, CIT = chemotherapy-induced thrombocytopenia, DC/CIK = dendritic cell–cytokine-induced killer cell.