Table 2.
Collagen expression, DNA content, and ROS in HSCs. The values were expressed as M ± SD, and the effect size statistic was assessed by partial eta squared in each group.
| Group parameter | Control | Nilotinib | Nilotinib + MSC-CM | Partial η2 | Sig. | |
|---|---|---|---|---|---|---|
| Collagen expression (OD) | Mean ± SEM | 0.80 ± 0.12 | 0.57 ± 0.12∗ | 0.34 ± 0.08∗, # | 0.818 | 0.006 |
| P 1 | 0.090 | 0.005 | ||||
| P 2 | 0.090 | |||||
| DNA content μg/100 mL cell lysate | Mean ± SEM | 508.9 ± 67.5 | 340.1 ± 76.6∗ | 244.2 ± 61.4∗, # | 0.791 | 0.009 |
| P 1 | 0.054 | 0.008 | ||||
| P 2 | 0.278 | |||||
| ROS (OD) | Mean ± SEM | 0.18 ± 0.077 | 0.37 ± 0.23∗ | 0.78 ± 0.09∗, # | 0.808 | 0.007 |
| P 1 | 0.332 | 0.006 | ||||
| P 2 | 0.035 | |||||
P: probability. ∗Significant compared to the control group. #Significant compared to the Nilotinib group. P1 value for the control group. P2 value for the Nilotinib group. η2: eta squared. Test: one-way ANOVA, post hoc Tukey, and effect size statistic were assessed by partial eta squared.