Figure 1.

Effect of rinse, mechanical control of biofilm, and disease on salivary flow rate. Statistical analyses were performed with a sample of 56 volunteers, 28 per group. ηp²: Partial eta squared. Data plotted as median and interquartile range (due to non-Gaussian distribution). To fulfill the ANOVA premises, we used the log10 transformation. Considering the presence of significant interactions, the main effects of the disease and biofilm were suppressed. A single asterisk represents a significant p-value ≤ 0.05. A double asterisk represents a p-value ≤ 0.01. Simple effects for Rinse in CF children—Mechanical control of biofilm: α = 0.01 (β-1 = 0.75) ηp² = 0.12 and No mechanical control of biofilm: α = 0.003 (β-1 = 0.86) ηp² = 0.15). Simple effects for Rinse in children with ECC—Mechanical control of biofilm: α = 0.002 (β-1 = 0.88) ηp² = 0.16 and No mechanical control of biofilm: α = 0.08 (β-1 = 0.42) ηp² = 0.06). Simple effects for Biofilm in CF children—Pre-rinse: α = 0.72 (β-1 = 0.07) ηp² = 0.002 and Post-rinse: α = 0.78 (β-1 = 0.06) ηp² = 0.002. Simple effects for Biofilm in children with ECC—Pre-rinse: α = 0.02 (β-1 = 0.69) ηp² = 0.103 and Post-rinse: α = 0.002 (β-1 = 0.88) ηp² = 0.16. Simple Effects for Disease: No significant effect considering a p-value > 0.05. Supplementary material provides complementary information regarding data statistics.