Table 1.

Effect of phase volume ratio on double encapsulation

Sl no	Phase composition (w/w %)/ carrier materials	Volume ratio	Before drying			After drying
			C-PC Purity (Top phase)	C-PC Purity (Bottom phase)	C-PC yield in top phase (%w/w)	C-PC yield in bottom phase (%w/w)	C-PC Purity (extracting phase)	C-PC yield in extracting phase (%w/w)
PEG 4000/potassium phosphate system
1	PEG/Salt (PEG 4% and salt 18%)	0.29	0.88 ± 0.04	0.18 ± 0.002	81.44 ± 0.65	14 ± 0.35	0.5 ± 0.02	78.93 ± 1.5
2	PEG/Salt (PEG 10% and Salt 16%)	0.09	0.76 ± 0.02	0.17 ± 0.01	25.05 ± 0.43	22.55 ± 0.9	0.47 ± 0.04	43.53 ± 0.75
3	PEG/Salt (PEG 13% and Salt 14%)	0.8	0.54 ± 0.17	0.08 ± 0.01	93.11 ± 0.51	5.41 ± 0.15	0.41 ± 0.01	60.36 ± 1.7
PEG 4000/Dextran system
4	PEG/Dextran (PEG 8% and dextran 5%)	1.33	0.65 ± 0.03	0.44 ± 0.002	42.51 ± 0.41	37.07 ± 1.56	0.4 ± 0.02	100 ± 1.62
5	PEG/Dextran (PEG 6% and dextran 10%)	0.25	0.41 ± 0.001	0.55 ± 0.05	9.74 ± 0.08	81.83 ± 2.48	0.43 ± 0.01	94.98 ± 1.4
6	PEG/Dextran (PEG 4% and dextran 13%)	2.33	0.43 ± 0.001	0.43 ± 0.02	58.24 ± 0.2	40.91 ± 0.65	0.4 ± 0.01	~ 100 ± 1.7
PEG 4000/Maltodextrin system
7	PEG/MDX (PEG 9.3% and MDX 36%)	No phase formation	–	–	–	–	–	–
8	PEG/MDX (PEG 12.3% and MDX 30%)	–	–	–	–	–	–	–
Maltodextrin Alone (conventional microencapsulation)
9	MDX alone	–	0.33 ± 0.02		22.45 ± 0.02 mg/g.db		0.32 ± 0.03	72.67 ± 0.34

_{Values are averages±standard deviation from three replicate (n=3) analyses}

*Crude extract has C-PC purity of 0.38