Table 3.
Moisture content and flow properties of double encapsulated C-PC powder samples
| Ser. No | Samples | Moisture (%,w/w) |
Flow properties | |
|---|---|---|---|---|
| Carr’s index* | Hausner’s ratio | |||
| Freeze drying | ||||
| 1 | PEG and salt (PEG 4% and salt 18%) | 5.2 ± 0.26 | 22 ± 1.1 | 1.13 ± 0.06 |
| 2 | PEG Dextran (PEG 6% and dextran10%) | 3.98 ± 0.2 | 30 ± 1.5 | 1.42 ± 0.07 |
| Spray drying | ||||
| 3 | PEG/Salt (PEG 4% and salt 18%) | 3.95 ± 0.19 | 35 ± 1.8 | 1.5 ± 0.075 |
| 4 | PEG/Salt (PEG 10% and Salt 16%) | 3.2 ± 0.16 | 33 ± 1.7 | 1.49 ± 0.75 |
| 5 | PEG/Salt (PEG 13% and Salt 14%) | 4.09 ± 0.20 | 38 ± 1.9 | 1.61 ± 0.08 |
| 6 | PEG/Dextran (PEG 8% and dextran 5%) | 5.12 ± 0.26 | 40 ± 2 | 1.6 ± 0.08 |
| 7 | PEG/Dextran (PEG 6% and dextran 10%) | 5.38 ± 0.27 | 39 ± 1.95 | 1.64 ± 0.07 |
| 8 | PEG/Dextran (PEG 4% and dextran 13%) | 4.98 ± 0.25 | 41 ± 2.05 | 1.69 ± 0.08 |
| 9 | Maltodextrin | 5.78 ± 0.29 | 40 ± 2 | 1.6 ± 0.08 |
Values are averages±standard deviation from three replicate (n = 3) analyses
* Range of Carr’s index value with its respective flow characteristics, 5–15: Excellent flow, 16–18: Good flow, 19–21: Moderately good flow, 22–35: Poor flow, 36–40: Very poor flow