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. 2021 Mar 23;15:649051. doi: 10.3389/fnhum.2021.649051

TABLE 1.

Demographic, clinical, and cognitive data of MSA and HC.

Demographic variable MSA-NCI (n = 25) MSA-MCI (n = 20) HC (n = 29) Z/χ2 p-value
Age (years) 62.52 ± 6.90 64.15 ± 9.22 61.17 ± 6.77 0.672 0.715
Sex (F:M) 12: 13 14: 6 20: 9 3.225 0.199
Education (years) 11.32 ± 3.18 11.70 ± 2.97 12.52 ± 3.10 2.040 0.361
Disease duration (years) 4.44 ± 2.10 3.80 ± 2.19 –1.254 0.210
MoCA 26.80 ± 1.22 20.10 ± 2.71 27.17 ± 1.23 46.454 0.000*
UMSARSII 7.24 ± 5.16 15.60 ± 2.76 4.592 0.000*
UMSARSIII 34.00 ± 13.59 38.90 ± 17.48 1.006 0.314

Variables are mean ± standard deviation: MSA, multiple system atrophy; MCI, mild cognitive impairment; NCI, no cognitive impairment; HC, healthy controls; MoCA, Montreal Cognitive Assessment; UMSARSII and UMSARSIII, Unified Multiple System Atrophy Rating Scale parts II and part III; p < 0.05 was considered statistically significant; 0.000*, values < 0.000.