TABLE 9.

Result of comparison with existing state-of-the-art methods in layer 1 (enhancers identification).

Method	ACC	AUC	SN	SP	MCC	Source
iEnhancer-2L	0.730	0.806	0.710	0.750	0.460	Liu B. et al., 2016
EnhancerPred	0.740	0.801	0.735	0.745	0.480	Jia and He, 2016
iEnhancer-EL	0.748	0.817	0.710	0.785	0.496	Liu B. et al., 2016; Liu G. et al., 2018
iEnhancer-ECNN	0.769	0.832	0.785	0.752	0.537	Nguyen et al., 2019
iEnhancer-EBLSTM	0.772	0.835	0.755	0.795	0.534	This study