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. 2021 Mar 23;9:649515. doi: 10.3389/fped.2021.649515

Table 1.

Criteria of SIMPLE scoring system.

0 1 2 3
Presence of maternal chorioamnionitis No Yes
Completed cure of antenatal steroid Yes No
Birth weight, (g) >1,250 1,000–1,250 750–1,000 <750
Cord blood gas base deficit (mmol/L) <−12 −12 to −16 >−16
*Presence of hypotension requiring inotropic support No Yes
*Presence of tachycardia (beat/min) <160 160–180 >180
*Need of invasive MV no yes HFOV
*#Presence of metabolic acidosis pH: >7.35 7.25–7.35 7.10–7.25 <7.1
BD: < −4 −4 to −10 −10 to −16 < −16
*Presence of respiratory acidosis (PCO2, mmHg) 35–45 45–55 55–65 >65
*Maximum PIP (cmH2O) <18 18–23 >23
PIP reduction % according to prior assessment >20% %10–20 <10%
FiO2 at admission (%) <40 40–60 >60
FiO2 reduction % according to prior assessment >20% 10%−20% <10%
Number of surfactant administered 0 1 >1
*

During evaluation episode.

#

The highest score will be given according to pH or BD.

BD, base deficit; HFOV, high frequency oscillatory ventilation; MV, mechanical ventilation; PIP, peak inspiratory pressure.