Table 6.

SIMPLE scores in infants with/without hemodynamically significant patent ductus arteriosus (hsPDA) by echocardiography.

Evaluation time	SIMPLE scores in infants with hsPDA (n = 30) median (range)	SIMPLE scores in infants without PDA (n = 18) median (range)	p-value
6 h	12 (5–19)	4 (2–18)	<0.001
12 h	13 (5–20)	4 (2–13)	0.001
18 h	13 (5–22)	4 (2–14)	<0.001
24 h	14 (5–19)	4 (2–14)	<0.001
48 h	15 (10–23)	4 (2–13)	<0.001
72 h	14 (9–21)	4 (2–12)	<0.001