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. 2021 Mar 23;8:622643. doi: 10.3389/fmolb.2021.622643

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Copyright © 2021 Budhwani, Turrell, Yu, Frazer, Mehdi and Chandra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High expression of multiple immune suppression genes is associated with increased 5-years survival probability with CESC. A custom built list of 50 immune suppressive genes including immune checkpoint inhibitor genes, Treg related genes and soluble mediators was analyzed for significant association with 5-years survival probability. (A) Number of genes where high or low expression was associated with increased 5-years survival probability. (B) p-values of significant immune suppression genes were −log10 transformed. Genes for which low expression was associated with increased survival probability were further transformed to a negative value.