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. 2021 Mar 23;12:649749. doi: 10.3389/fneur.2021.649749

Table 3.

Neonatal short-term complications and mortality by preterm birth subtype.

Spontaneous (n = 1,038) Iatrogenic (n = 651) Total (n = 1,689) P-value
RDS 986 (95.0%) 627 (96.3%) 1,613 (95.5%) 0.202
Pneumonia 657 (63.3%) 434 (66.7%) 1,091 (64.6%) 0.158
Severe anemia 587 (56.6%) 372 (57.1%) 959 (56.8%) 0.811
PPHN 247 (23.8%) 156 (24.0%) 403 (23.9%) 0.937
PDA 400 (38.5%) 250 (38.4%) 650 (38.5%) 0.956
NEC (II-III) 28 (2.7%) 42 (6.5%) 70 (4.1%) 0.000
ROP 22 (2.1%) 17 (2.6%) 39 (2.3%) 0.512
BPD 366 (35.3%) 234 (35.9%) 600 (35.5%) 0.775
Cholestasis 156 (15.0%) 100 (15.4%) 256 (15.2%) 0.853
IVH 363 (35.0%) 193 (29.6%) 556 (32.9%) 0.023
IVH(III-IV) 65 (6.3%) 25 (3.8%) 90 (5.3%) 0.031
Coagulopathy 123 (11.8%) 118 (18.1%) 241 (14.3%) 0.000
PVL 37 (3.6%) 19 (2.9%) 56 (3.3%) 0.471
Pathoglycemia 8 (0.8%) 14 (2.2%) 22 (1.3%) 0.015
In-hospital death 197 (19.0%) 128 (19.7%) 325 (19.2%) 0.729
<28w 73 (48.0%) 19 (55.9%) 92 (49.5%) 0.408
28–29+6 w 83 (19.8%) 52 (23.0%) 135 (20.9%) 0.341
30–31+6 w 41 (8.8%) 57 (14.6%) 98 (11.4%) 0.008

RDS, respiratory distress syndrome; PPHN, persistent pulmonary hypertension; PDA, patent ductus arteriosus; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity; BPD, bronchopulmonary dysplasia; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia.