TABLE 2.
Characteristics of study participants
Subjects | 14 |
Age years | 54 (36–70) |
Female/male | 8/6 |
Smoking status (never/past/current) | 10/4/0 |
Body mass index kg·m−2 | 24.2 (22.1–31.0) |
Asthma-onset age years | 37 (10–55) |
Asthma duration years | 17 (5–35) |
Type 2 inflammation (no/yes)# | 0/14 |
Asthma Control Test score¶ | 18 (12–22) |
FEV1 % pred¶ | 68 (51–89) |
Fixed airflow obstruction+ | 8 |
Chronic rhinosinusitis¶ | 8 |
Frequency of exacerbations in the last 12 months¶ | 3 (2–8) |
Frequency of emergency room visits or hospitalisations for asthma exacerbation in the last 12 months¶ | 2 (0–6) |
Asthma treatment step¶ | |
GINA step 4 | 4 |
GINA step 5 | 10 |
Number of patients taking OCS¶ | 14 |
Taking OCS as needed | 5 |
Taking OCS maintenance | 9 |
Total OCS dose in the last 12 months mg§ | 900 (420–2775) |
Data are presented as n or median (range). FEV1: forced expiratory volume in 1 s; % pred: % predicted; GINA: Global Initiative for Asthma; OCS: oral corticosteroid. #: defined as yes if the patient had at least one of the following: induced sputum eosinophils ≥3%, blood eosinophils ≥450 cell·µL−1 or fractional exhaled nitric oxide ≥30 ppb. ¶: information at the time of recruitment. +: defined by postbronchodilator FEV1 % pred <70%. §: prednisolone-equivalent dose.