Table 1.
Correlation analysis of CD274/PDCD1LG2 expression with mismatch repair (MMR) and DNA methyltransferase (DNMT).
| Tumor | Spearman | MMR | DNMT | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| EPCAM | MLH1 | MSH2 | MSH6 | PMS2 | DNMT1 | DNMT3A | DNMT3B | |||
| CD274 | CHOL | R | −0.18816 | 0.453539 | 0.289318 | 0.400772 | 0.235521 | 0.359917 | −0.18746 | −0.21202 |
| CHOL | P-value | 0.333454 | 0.027339 | 0.260987 | 0.061694 | 0.333454 | 0.093221 | 0.4289 | 0.4289 | |
| COAD | R | −0.17445 | −0.07269 | 0.119258 | 0.249567 | 0.024473 | 0.144956 | −0.0889 | −0.08137 | |
| COAD | P-value | 0.000702 | 0.240673 | 0.031913 | 3.11E-07 | 0.601398 | 0.00561 | 0.114561 | 0.114561 | |
| ESCA | R | −0.32706 | 0.009353 | −0.08905 | 0.026681 | −0.11629 | 0.041869 | −0.148 | −0.07887 | |
| ESCA | P-value | 0.000108 | 1 | 0.779336 | 1 | 0.56227 | 0.636896 | 0.180519 | 0.636896 | |
| LIHC | R | −0.02565 | 0.323872 | 0.276122 | 0.268484 | 0.287001 | 0.490804 | 0.09953 | 0.08108 | |
| LIHC | P-value | 0.621419 | 7.39E-10 | 1.78E-07 | 2.81E-07 | 6.67E-08 | 1.57E-23 | 0.109575 | 0.117999 | |
| PAAD | R | −0.10438 | 0.533641 | 0.48648 | 0.576787 | 0.36405 | 0.496813 | 0.213342 | 0.163804 | |
| PAAD | P-value | 0.165564 | 6.89E-14 | 1.74E-11 | 1.79E-16 | 1.17E-06 | 5.24E-12 | 0.008492 | 0.028903 | |
| READ | R | 0.042965 | 0.329019 | 0.355855 | 0.428334 | 0.300045 | 0.225528 | 0.128959 | 0.056493 | |
| READ | P-value | 0.581419 | 4.25E-05 | 9.46E-06 | 3.86E-08 | 0.000163 | 0.010155 | 0.193449 | 0.468364 | |
| STAD | R | 0.020888 | 0.151739 | 0.287854 | 0.392907 | 0.293081 | 0.183127 | 0.040141 | −0.03326 | |
| STAD | P-value | 0.686804 | 0.006445 | 4.13E-08 | 1.36E-14 | 2.92E-08 | 0.001093 | 0.876637 | 0.876637 | |
| PDCD1LG2 | CHOL | R | −0.21905 | 0.430888 | 0.248649 | 0.385328 | 0.306821 | 0.351351 | −0.09472 | −0.10579 |
| CHOL | P-value | 0.287307 | 0.043513 | 0.287307 | 0.08119 | 0.206213 | 0.106864 | 1 | 1 | |
| COAD | R | −0.17776 | 0.065562 | 0.142451 | 0.236716 | 0.122061 | 0.161801 | 0.021428 | −0.05155 | |
| COAD | P-value | 0.000525 | 0.161284 | 0.006733 | 1.49E-06 | 0.017852 | 0.001526 | 0.647399 | 0.541866 | |
| ESCA | R | −0.44693 | 0.157969 | 0.000631 | 0.148759 | 0.020448 | 0.146261 | 0.01071 | 0.105305 | |
| ESCA | P-value | 1.25E-08 | 0.17871 | 1 | 0.17871 | 1 | 0.189854 | 0.892398 | 0.36464 | |
| LIHC | R | 0.030398 | 0.231375 | 0.157928 | 0.181724 | 0.16655 | 0.273517 | 0.057927 | 0.053573 | |
| LIHC | P-value | 0.558383 | 3.17E-05 | 0.00444 | 0.001679 | 0.003735 | 2.4E-07 | 0.528893 | 0.528893 | |
| PAAD | R | −0.32388 | 0.493875 | 0.324009 | 0.537676 | 0.331045 | 0.472252 | 0.249401 | 0.063617 | |
| PAAD | P-value | 2.05E-05 | 9.87E-12 | 2.05E-05 | 5.02E-14 | 1.91E-05 | 8.5E-11 | 0.001575 | 0.398879 | |
| READ | R | −0.07558 | 0.287624 | 0.182248 | 0.258266 | 0.294101 | 0.125439 | 0.082768 | 0.01599 | |
| READ | P-value | 0.331687 | 0.000656 | 0.036821 | 0.002257 | 0.000572 | 0.318773 | 0.575208 | 0.837492 | |
| STAD | R | −0.20015 | 0.279894 | 0.159715 | 0.333779 | 0.277346 | 0.350788 | 0.15516 | −0.11656 | |
| STAD | P-value | 0.00019 | 1.41E-07 | 0.001919 | 1.64E-10 | 1.43E-07 | 8.03E-12 | 0.005175 | 0.023985 | |