Table 2.
Age effects on intrinsic connectivity and hemodynamics.
| Anatomical region | Low ICC | Hemodynamic lead | ||
|---|---|---|---|---|
| Group effect (p)a | Correlation with age (r, p)a | Group effect (p)a | Correlation with age (r, p)a | |
| Old>Young | Old>Young | |||
| IFG | 0.002 | 0.407 (0.001) | ||
| vmPFC | 0.01 | 0.395 (0.002)b | 0.0012 | 0.535 (<0.001)b |
| dlPFC | 0.01 | 0.387 (0.002) | ||
| SMA | 0.001 | 0.440 (0.001) | 0.01 | 0.380 (0.002) |
| PCC | 0.002 | 0.320 (0.01) | ||
| Temporal pole | 0.001 | 0.469 (<0.001)b | ||
| Insula | 0.005 | 0.398 (0.001) | ||
| Putamen | 0.001 | 0.508 (<0.001) | ||
| Thalamus | 0.01 | 0.545 (<0.001)b | ||
| Old < Young | Old < Young | |||
| Inferior occipital gyrus | 0.001 | −0.544 (<0.001) | 0.001 | −0.518 (<0.001)b |
a
Controlling for gender and education in years.
b
Remained significant (p <0.002) after controlling for depression symptoms.