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. 2021 Mar 23;8:664718. doi: 10.3389/fvets.2021.664718

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Copyright © 2021 Chibuk, Flory, Kruglyak, Leibman, Nahama, Dharajiya, van den Boom, Jensen, Friedman, Shen, Clemente-Vicario, Chorny, Tynan, Lytle, Holtvoigt, Murtaza, Diaz Jr., Tsui and Grosu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular pathways and functional processes involved in cancer. Driver mutations in cancer-related genes are responsible for cancer development. These cancer-related genes are implicated in 12 cellular signaling pathways, which can be grouped into 3 core cellular functions: cell survival, cell fate, and genome maintenance [Inspired by Hanahan & Weinberg (2011) and Vogelstein et al. (2013)] (58, 68).