Table 1.
Baseline characteristics of the SFTS patients and healthy residents.
| Patient | Age (year)/Sex | Date of sampling (onset) | CCI* | Route of infection | Outcome | ANC (/μl) | PLT (/103 μl) | AST (IU/L) | ALT (IU/L) | CK (IU/L) | LDH (IU/L) | aPTT (/sec) | MODS† | FRNT50 titer |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jeju-P01 | 73/M | May-16-13 (May-02-13) |
0 | Tick | Death | 724 | 30 | 392 | 136 | 4,377 | 2,177 | 74 | 19 | 6.57 |
| Jeju-P04 | 62/M | Jun-13-13 (Jun-05-13) |
0 | Tick | Death | 815 | 55 | 524 | 152 | 588 | 1,481 | 51 | 16 | 6.22 |
| Jeju-P16 | 74/M | Jun-10-15 (Jun-07-15) |
1 | Tick | Death | 1530 | 47 | 157 | 56 | 345 | 1,071 | 53 | 13 | 0 |
| Jeju-P48 | 71/M | May-02-18 (April-07-18) |
2 | Tick | Death | 4,280 | 214 | 51 | 16 | 359 | N/A | 26 | 11 | 7.73 |
| Jeju-P49-1 | 81/F | Jun-12-18 (Jun-06-18) |
1 | Tick | Recovery | 250 | 64 | 35 | 33 | 1,030 | 615 | 35 | 3 | 3.40 |
| -2 | Jun-14-18 | 190 | 22 | 368 | 112 | 862 | 2242 | 48 | 4 | 2.17 | ||||
| -3 | Jun-16-18 | 120 | 38 | 314 | 118 | 339 | 1353 | 31 | 4 | 0.60 | ||||
| -4 | Jun-18-18 | 1,000 | 74 | 265 | 155 | 111 | 1,177 | 30 | 3 | 9.89 | ||||
| -5 | Jun-20-18 | 2,010 | 147 | 258 | 185 | 69 | 854 | N/A | 2 | 2.80 | ||||
| Jeju-P55 | 68/M | Oct-11-18 (Oct-08-18) |
1 | Tick | Death | 317 | 55 | 713 | 130 | 455 | 8,559 | 713 | 12 | 0 |
| Jeju-P57-1 | 37/F | Oct-21-18 (Oct-21-18) |
0 | Patient | Recovery | 1,100 | 168 | 33 | 16 | 62 | 380 | 33 | 1 | 2.48 |
| -2 | Dec-24-18 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 105.3 | ||||
| -3 | Oct-17-19 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 123.4 | ||||
| Jeju-P63 | 92/F | July-05-19 (Jun-06-19) |
1 | Tick | Death | 1,230 | 90 | 34 | 84 | 323 | 1,013 | 34 | 7 | 1.11 |
| Jeju-P64 | 64/M | Aug-12-19 (Aug-07-19) |
0 | Tick | Recovery | 260 | 62 | 36 | 78 | N/A | 571 | 36 | 2 | 0 |
| Jeju-P66-1 | 60/M | Aug-28-19 (Aug-24-19) |
1 | Tick | Recovery | 890 | 128 | 33 | 45 | 106 | 657 | 33 | 1 | 10.25 |
| -2 | Aug-30-19 | 450 | 108 | 80 | 56 | 589 | 172 | 30 | 1 | 5.86 | ||||
| Jeju-P70-1 | 70/F | Oct-11-19 (Oct-10-19)- |
0 | Tick | Recovery | 3,460 | 79 | 38 | 21 | N/A | 682 | 38 | 10 | 13.53 |
| -2 | Oct-22-19 | 12,370 | 76 | 21 | 21 | N/A | 647 | 34 | 11 | 34.82 | ||||
| Jeju-H10 | 77/F | Nov-24-15 (N/A) |
3 | N/A | Healthy | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 31.52 |
| Jeju-H13 | 67/M | Nov-24-15 (N/A) |
0 | N/A | Healthy | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 24.88 |
| Jeju-H17 | 78/M | Nov-24-15 (N/A) |
0 | N/A | Healthy | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 24.25 |
| Jeju-H21-1 | 56/F | Nov-11-15 (N/A) |
0 | N/A | Healthy | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 129.4 |
| -2 | July-28-16 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 67.67 | ||||
| -3 | April-30-17 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 96.84 | ||||
| Jeju-H22 | 71/F | Nov-24-15 (N/A) |
0 | N/A | Healthy | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | 104.7 |
M, male; F, female; *CCI, Charlson comorbidity index score, predicts the 10-year mortality for a patient who may have a range of comorbid conditions; SFTS, severe fever with thrombocytopenia syndrome; ANC, absolute neutrophil count; PLT, platelet; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CK, creatinine kinase; LDH, lactate dehydrogenase; aPTT, activated partial thromboplastin time; †MODS, multiple organ dysfunction syndrome score, constructed using simple physiologic measures of dysfunction in six organ systems, mirrors organ, and correlates strongly with the ultimate risk of intensive care unit mortality and hospital mortality; N/A, not applicable.