Table 4.

Acute and late radiation toxicities by treatment group.

	APBI (N = 173)								AWBI (N = 300)
	Grade 1		Grade 2		Grade 3		Total		Grade 1		Grade 2		Grade 3		Total
Acute period
Dermatitis	80	(46.2%)	3	(1.7%)	0	(0.0%)	83	(48.0%)	205	(68.3%)	24	(8.0%)	0	(0.0%)	229	(76.3%)
Breast swelling	7	(4.0%)	0	(0.0%)	0	(0.0%)	7	(4.0%)	168	(56.0%)	0	(0.0%)	0	(0.0%)	168	(56.0%)
Breast pain	33	(19.1%)	1	(0.6%)	0	(0.0%)	34	(19.7%)	101	(33.7%)	13	(4.3%)	0	(0.0%)	114	(38.0%)
Fatigue	14	(8.1%)	0	(0.0%)	0	(0.0%)	14	(8.1%)	72	(24.0%)	2	(0.7%)	0	(0.0%)	74	(24.7%)
Nausea	8	(4.6%)	3	(1.7%)	0	(0.0%)	11	(6.4%)	15	(5.0%)	6	(2.0%)	0	(0.0%)	21	(7.0%)
Late period
Breast pain	74	(42.8%)	3	(1.7%)	0	(0.0%)	77	(44.5%)	110	(36.7%)	21	(7.0%)	0	(0.0%)	131	(43.7%)
Pigmentation	43	(24.9%)	0	(0.0%)	0	(0.0%)	43	(24.9%)	142	(47.3%)	2	(0.7%)	0	(0.0%)	144	(48.0%)
Breast swelling	9	(5.2%)	0	(0.0%)	0	(0.0%)	9	(5.2%)	117	(39.0%)	8	(2.7%)	0	(0.0%)	125	(41.7%)
Dermatitis	30	(17.3%)	5	(2.9%)	0	(0.0%)	35	(20.2%)	30	(10.0%)	19	(6.3%)	2	(0.7%)	51	(17.0%)
Fibrosis	16	(9.2%)	0	(0.0%)	0	(0.0%)	16	(9.2%)	35	(11.7%)	2	(0.7%)	0	(0.0%)	37	(12.3%)
Rib change	9	(5.2%)	0	(0.0%)	0	(0.0%)	9	(5.2%)	14	(4.7%)	0	(0.0%)	0	(0.0%)	14	(4.7%)
Telangiectasia	5	(2.9%)	1	(0.6%)	0	(0.0%)	6	(3.5%)	13	(4.3%)	0	(0.0%)	0	(0.0%)	13	(4.3%)
Lymphedema	4	(2.3%)	0	(0.0%)	0	(0.0%)	4	(2.3%)	10	(3.3%)	0	(0.0%)	0	(0.0%)	10	(3.3%)
Pneumonitis	0	(0.0%)	2	(1.2%)	0	(0.0%)	2	(1.2%)	0	(0.0%)	6	(2.0%)	3	(1.0%)	9	(3.0%)
Fatty necrosis	4	(2.3%)	0	(0.0%)	0	(0.0%)	4	(2.3%)	4	(1.3%)	0	(0.0%)	0	(0.0%)	4	(1.3%)

APBI, accelerated partial breast irradiation; AWBI, accelerated whole-breast irradiation.