. 2021 Feb 1;6(2):93–100. doi: 10.1302/2058-5241.6.200118

Table 1.

Techniques applied in prosthetic joint infection novel diagnostic strategies

Cultures^21–26

– Culturing after sonication/rinsing

– Culturing in blood-culture enriched media

Imaging techniques^27–29

– Fluorescent in situ hybridization (FISH)

– Confocal laser scanning microscopy (CLSM)

– Scanning electron microscopy (SEM)

Biomolecular techniques^30–36

– PCR-based methods, including multiplex PCR and DNA microarrays

– Electrospray ionization (ESI-TOF) and matrix-assisted laser desorption ionization (MALDI-TOF) time of flight mass spectrometry

– Fourier transformed near infrared (FT-NIR) spectroscopy

– Next-generation sequencing (NGS) based on shotgun metagenomics

Note. PCR, polymerase chain reaction.