TABLE 1.
Demographics of patients undergoing estrogen replacement therapy
| Total | Increasing dose | Constant dose | P value | |
|---|---|---|---|---|
| n | 639 | 315 | 324 | |
| Female age (years) | 36.8 ± 4.7 | 37.0 ± 4.8 | 36.6 ± 4.7 | .419 a |
| Primary infertility | 228 (35.7) | 118 (37.5) | 110 (34.0) | .354 b |
| Secondary infertility | 411 (64.3) | 197 (62.5) | 214 (66.0) | |
| Indication of ART | ||||
| Tubal factor | 58 (9.1) | 29 (9.2) | 29 (9.0) | .910 a |
| Endometriosis | 58 (9.1) | 27 (8.6) | 31 (9.6) | .661 a |
| Ovulation disorder | 37 (5.8) | 18 (5.7) | 19 (5.9) | .935 a |
| Male factor | 167 (26.1) | 90 (28.6) | 77 (23.8) | .166 a |
| Unexplained infertility | 260 (40.7) | 120 (38.1) | 140 (43.2) | .188 a |
| Primipara | 374 (58.5) | 196 (62.2) | 178 (54.9) | .061 b |
| Multipara | 265 (41.5) | 119 (37.8) | 146 (45.1) | |
| Recurrent pregnancy loss | 88 (13.8) | 44 (14.0) | 44 (13.6) | .886 b |
| Body mass index (kg/m2) | 21.2 ± 2.8 | 21.2 ± 2.9 | 21.2 ± 2.8 | .624 a |
| Serum AMH (ng/mL) | 3.2 ± 8.4 | 3.5 ± 12.0 | 2.8 ± 4.8 | .201 a |
| No. of previous ET cycles | 2.3 ± 13.6 | 2.4 ± 12.2 | 2.3 ± 15.0 | .442 a |
Data are expressed as mean ± standard deviation or number (%).
Abbreviations: AMH, anti‐Müllerrian hormone; ART, assisted reproductive technology; ET, embryo transfer.
a
Mann‐Whitney U test.
b
Pearson's chi‐square test.