TABLE 2.
Demographic and treatment parameters in the four cohorts
| Parameter | UI (1) (103) | UI (2) (86) | UI (3) (114) | Controls (418) | P value |
|---|---|---|---|---|---|
| Age (y) (Mean ± SD) | 33.59 ± 4.14 | 33.23 ± 4.11 | 33.2 ± 4.7 | 31.99 ± 4.25 | .001 |
| Infertility duration Median (IQR) | 6 (4.5‐10) | 6 (4‐9.1) | 5 (3‐8) | 6 (4‐9) | .033 |
| Cycles with Previous live‐births n (%) | 9 (8.7) | 15 (17.44) | 13 (11.2) | 62 (14.8) | .00 |
| BMI Kg/m2 (Mean ± SD) | 26.29 ± 3.57 | 26.71 ± 5.06 | 25.5 ± 4.01 | 25.54 ± 4.13 | .058 |
| Cycles with previous ≥1 failed IUI. n (%) | 87 (84.5) | 52 (60.5) | 87 (76.3) | 104 (24.9) | <.001 |
| Previous IUIs Median (Range) | 3 (0‐12) | 2 (0‐10) | 2 (0‐19) | 0 (0‐4) | <.001 |
| Previous Failed IVFs n (%) | 30 (29.1%) | 22 (25.6%) | 21 (18.4%) | 101 (24.2%) | .31 |
| AMH ng/mL Median (IQR) | 3.9 (1.6‐6.3) | 2.6 (1.2‐4.0) | 2.2 (1.1‐4.6) | 2.57 (1.4‐4.3) | .00 |
| Total dose Median (IQR) IU | 1575 (1200‐2250) | 1775 (1400‐2212) | 1650 (950‐2877) | 1612 (1325‐1612) | .51 |
| Estradiol Median (IQR) pg/mL | 1900 (1082‐2837) | 2004 (1165‐2993) | 1746 (950‐2877) | 1907 (932‐2355) | .074 |
|
Endometrial thickness (mm) Mean ± SD |
8.96 ± 2.05 | 8.97 ± 2.04 | 8.6 ± 1.7 | 8.34 ± 1.95 | .01 |
Gaussian variables expressed as mean ± SD. Non‐Gaussian as median (interquartile range) or median (range). Categorical variables expressed as number and percentage