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. 2021 Apr 5;181(7):997–1000. doi: 10.1001/jamainternmed.2021.0488

Table 1. Characteristics of Participants With Symptoms (n = 220 588) by SARS-CoV-2 and Venous Thromboembolism (VTE) Status.

Characteristic Patients, No. (%)
SARS-CoV-2 positive SARS-CoV-2 negative
No VTE (n = 25 906) VTE (n = 198) No VTE (n = 193 476) VTE (n = 1008)
Age, y
18-29 5925 (23) 14 (7) 34 180 (18) 28 (3)
30-39 5670 (22) 19 (10) 41 102 (21) 47 (5)
40-49 5451 (21) 38 (19) 36 432 (19) 89 (9)
50-59 4682 (18) 48 (24) 33 676 (17) 152 (15)
60-69 2655 (10) 40 (20) 25 593 (13) 245 (24)
70-79 984 (4) 26 (13) 14 382 (7) 234 (23)
≥80 539 (2) 13 (7) 8111 (4) 213 (21)
Median (IQR) 42 (31-55) 56 (45-67) 46 (34-60) 68 (56-78)
Sex
Women 13 649 (53) 79 (40) 116 837 (60) 510 (51)
Men 12 257 (47) 119 (60) 76 639 (40) 498 (49)
Race/ethnicity
Asian 3176 (12) 30 (15) 32 310 (17) 116 (12)
Black 1767 (7) 25 (13) 13 857 (7) 105 (10)
Hispanic 13 116 (51) 88 (44) 46 857 (24) 127 (13)
White 5667 (22) 45 (23) 84 398 (44) 615 (61)
Missing/other 2180 (8) 10 (5) 16 054 (8) 45 (4)
BMI
Underweight 163 (1) 1 (0) 2616 (1) 24 (2)
Healthy weight 4588 (18) 23 (12) 55 413 (29) 256 (25)
Overweight 7963 (31) 56 (28) 62 134 (32) 303 (30)
Obese 12 086 (47) 110 (56) 69 244 (36) 417 (41)
Unknown 1106 (4) 8 (4) 4069 (2) 8 (1)
Median (IQR) 30 (26-34) 31 (28-36) 28 (24-32) 29 (24-34)
Comorbidities
Hypertension 2563 (10) 98 (49) 25 151 (13) 611 (61)
Diabetes 2672 (10) 71 (36) 18 493 (10) 322 (32)
Chronic kidney disease 901 (3) 28 (14) 11 056 (6) 273 (27)
COPD/asthma 2254 (9) 38 (19) 28 058 (15) 300 (30)
Congestive heart failure 364 (1) 22 (11) 6128 (3) 256 (25)
Liver cirrhosis 69 (0) 3 (2) 1029 (1) 38 (4)
Malignant neoplasm 397 (2) 15 (8) 8592 (4) 298 (30)
Charlson Comorbidity Index score
0 18 428 (71) 96 (48) 122 256 (63) 264 (26)
1-2 5698 (22) 66 (33) 48 548 (25) 271 (27)
3-4 986 (4) 16 (8) 11 429 (6) 193 (19)
≥5 794 (3) 20 (10) 11 243 (6) 280 (28)
Median (IQR) 0 (0-1) 1 (0-2) 0 (0-1) 2 (0-5)
Smoking status
Ever 6597 (25) 58 (29) 66 075 (34) 491 (49)
Never 18 367 (71) 131 (66) 124 209 (64) 510 (51)
Unknown 942 (4) 9 (5) 3192 (2) 7 (1)
Test month
February-April 2068 (8) 46 (23) 28 428 (15) 201 (20)
May 979 (4) 9 (5) 32 579 (17) 235 (23)
June 3354 (13) 25 (13) 28 577 (15) 165 (16)
July 12 185 (47) 70 (35) 61 153 (32) 217 (22)
August 7320 (28) 48 (24) 42 739 (22) 190 (19)
Laboratory test setting
Outpatient 22 209 (86) 95 (48) 168 780 (87) 190 (19)
Emergency department 2420 (9) 22 (11) 12 997 (7) 107 (11)
Inpatient 1277 (5) 81 (41) 11 699 (6) 711 (71)
Highest level of follow-up care
Outpatient/emergency department 23 092 (89) 28 (14) 172 713 (89) 114 (11)
Inpatient 2252 (9) 82 (41) 18 479 (10) 645 (64)
Intensive care unit 562 (2) 88 (44) 2284 (1) 249 (25)

Abbreviations: BMI, body mass index calculated as weight in kilograms divided by height in meters squared; COPD, chronic obstructive pulmonary disease; IQR, interquartile range.