Table 3.
SAR at X3 position
 | ||
|---|---|---|
| Compound | X3 | IC50 (μM) |
| 27 |  |
9.0 |
| 28 |  |
6.9 |
| 29 |  |
1.9 |
| 30 |  |
1.0 |
| 31 |  |
3.8 |
| 32 |  |
3.9 |
| 33 |  |
3.0 |
| 34 |  |
17.9 |
| 35 |  |
5.4 |
| 36 |  |
2.6 |
| 37 |  |
1.5 |
| 38 |  |
1.0 |
| 39 |  |
0.65 |
*
Racemic compound
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