TABLE 1.
Pt No. | Age (yrs), Sex | Flandedness | Age of Onset | Epilepsy Type | Ictal Onset Zone | MRI Findings | AEDs | Comorbidities; SSRI Tx | SUDEP Risk | No. of Clinical Sz | No. of Sz w/Interpretable Resp Signal | No. of Sz w/Apnea |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 36, M | Rt | 2 | Rt TLE | Mesial HC | MTS, perinatal ischemia | Oxcarbazepine, topiramate, pregabalin, clonazepam | Anxiety & ADHD; N | High | 5 | 1 | 1 |
2 | 48, M | Rt | 37 | Rt TLE | Pst/mesial HC | None | Levetiracetam, lamotrigine, oxcarbazepine | OSA & depression; Y | Low | 12 | 4 | 3 |
3 | 35, F | Rt | 32 | Rt TLE | Mesial temp | FCD* | Levetiracetam, clonazepam | None; N | Low | 4 | 1 | 1 |
4 | 28, F | Rt | 1 | Lt TLE | Ant basal temp | MTS & FCD* | Lamotrigine, topiramate, levetiracetam | None; N | High | 4 | 2 | 2 |
5 | 59, F | Rt | 12 | Lt TLE | Mesial temp | None | Valproic acid, lacosamide, primidone | None; N | High | 9 | 9 | 9 |
6 | 34, M | Rt | 24 | Lt TLE | Pst basal temp | Likely FCD | Levetiracetam, carbamazepine | None; N | Low | 5 | 2 | 0 |
7 | 26, F | Rt | 9 | Lt TLE | Ant HC | MTS | Levetiracetam, lamotrigine, carbamazepine, zonisamide | Depression; Y | High | 12 | 1 | 0 |
8 | 25, F | Rt | 22 | Lt TLE | Ant basal temp | FCD* | Levetiracetam, lamotrigine | Anxiety; Y | Low | 4 | 2 | 1 |
ADHD = attention deficit hyperactivity disorder; AED = anti-epileptic drug; Ant = anterior; FCD = focal cortical dysplasia; HC = hippocampus; MTS = mesial temporal sclerosis; N = no; OSA = obstructive sleep apnea; pst = posterior; pt = patient; resp = respiratory; SSRI = selective serotonin reuptake inhibitor; Sz = seizure(s); temp = temporal; Tx = therapy; Y = yes.
Confirmed on pathological examination.