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. 2021 Apr 6:1–15. doi: 10.1080/07420528.2021.1903027

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Figure 5. — The crystal structure of SARS-CoV-2 M^pro in complex with CX-4945. (a) A cartoon presentation of M^pro-inhibitor complex. (b) Surface presentation of M^pro. CX-4945 is presented in green color sticks. (c) A zoomed view of substrate-binding pocket representing the key amino acid residues forming interactions with inhibitor molecule. (d) Surface presentation of conserved substrate-binding pocket of SARS-CoV-2 M^pro