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. 2021 Mar 26;6(10):3596–3607. doi: 10.1016/j.bioactmat.2021.03.022

Fig. 8.

Fig. 8

The functionalized GelMA microspheres delay the progression of osteoarthritis in vivo. (a) Representative images of H&E staining and Safranin O-fast green staining in the histological staining assay display the histological changes in various degrees of cartilage section for different groups of rats at 8 weeks after the DMM surgery. The black arrow shows erosion fissures, and the black triangle represents tissue cellularity with cloning. (b) The corresponding depth of cartilage lesions, (c) relative GAG content and (d) OARSI score of articular cartilage in different groups of rats. (n = 5, * and # represent P < 0.05 by comparing with the sham and PBS groups, respectively).