Table 1. Frequency of spontaneously reported adverse events by session type in three PTSD patients.
| Session type | Preparatory | MDMA | Within 7 days after MDMA sessions | Other integrative sessions | Total |
|---|---|---|---|---|---|
| Total number of sessions | 9 | 9 | 9* | 18 | 45† |
| Abdominal pain | 4 | 1 | 1 | 0 | 6 |
| Anguish | 3 | 2 | 10 | 6 | 21 |
| Anxiety | 5 | 0 | 0 | 2 | 7 |
| Chest pain | 1 | 0 | 0 | 0 | 1 |
| Colic | 3 | 2 | 0 | 2 | 7 |
| Cough | 3 | 3 | 2 | 3 | 11 |
| Crying | 0 | 0 | 0 | 2 | 2 |
| Depression | 1 | 0 | 0 | 1 | 2 |
| Despair | 0 | 1 | 0 | 1 | 2 |
| Diarrhea | 1 | 0 | 0 | 0 | 1 |
| Dizziness | 1 | 1 | 0 | 0 | 2 |
| Drowsiness | 2 | 0 | 0 | 0 | 2 |
| Fear | 3 | 0 | 1 | 3 | 7 |
| Frustration | 1 | 0 | 0 | 0 | 1 |
| Headache | 2 | 0 | 3 | 1 | 6 |
| Impotence | 2 | 0 | 0 | 0 | 2 |
| Insomnia | 0 | 1 | 0 | 0 | 1 |
| Irritability | 0 | 1 | 0 | 1 | 2 |
| Jaw tension | 1 | 0 | 0 | 0 | 1 |
| Lack of libido | 0 | 0 | 0 | 1 | 1 |
| Lack of trust | 0 | 0 | 0 | 1 | 1 |
| Loneliness | 0 | 0 | 0 | 2 | 2 |
| Muscle tension | 0 | 0 | 1 | 1 | 2 |
| Nasal congestion | 0 | 1 | 0 | 0 | 1 |
| Nausea | 1 | 0 | 0 | 1 | 2 |
| Nightmares | 1 | 0 | 1 | 1 | 3 |
| Panic | 2 | 0 | 0 | 1 | 3 |
| Rage | 0 | 1 | 0 | 2 | 3 |
| Ruminative thoughts | 1 | 0 | 0 | 0 | 1 |
| Sadness | 3 | 1 | 0 | 2 | 6 |
| Fear | 0 | 0 | 0 | 1 | 1 |
| Shortness of breath | 1 | 0 | 0 | 0 | 1 |
| Sleeplessness | 0 | 0 | 1 | 0 | 1 |
| Somatic pains | 7 | 4 | 3 | 8 | 22 |
| Stress | 1 | 0 | 0 | 0 | 1 |
| Fatigue | 3 | 1 | 3 | 2 | 9 |
| Vulnerability | 1 | 0 | 0 | 2 | 3 |
| Total | 54 | 20 | 26 | 47 | 147 |
MDMA = 3,4-methylenedioxymethamphetamine; PTSD = Post-traumatic stress disorder.
*
Plus 63 phone contacts, daily during the first week post MDMA sessions.
†
Not counting phone contacts.