Table 3.
Multivariable analysis of factors predictive of the risk of death at 30 days and 6 months.
30-day risk of death |
6-month risk of death |
|
---|---|---|
HR (95% CI) | HR (95% CI) | |
Area | ||
Other EU | 1 | 1 |
UK | 1.52 (1.17–1.99) | 1.41 (1.10–1.80) |
Gender | ||
Male | 1 | 1 |
Female | 1.09 (0.82–1.45) | 1.12 (0.86–1.45) |
Age | ||
<65 years | 1 | 1 |
≥65 years | 1.76 (1.30–2.39) | 1.60 (1.23–2.10) |
Number of comorbidities | ||
0–1 | 1 | 1 |
≥2 | 1.34 (1.02–1.76) | 1.50 (1.17–1.92) |
Smoking history | ||
Never-smokers | 1 | 1 |
Current/former smokers | 1.18 (0.92–1.52) | 1.18 (0.93–1.48) |
Cancer site | ||
Breast | 0.84 (0.51–1.37) | 0.84 (0.54–1.32) |
Gastrointestinal | 1.08 (0.74–1.57) | 1.22 (0.86–1.71) |
Gynaecological/genitourinary | 0.89 (0.61–1.28) | 0.94 (0.67–1.33) |
Haematological | 1.29 (0.82–2.04) | 1.20 (0.78–1.85) |
Lung | 1 | 1 |
Other | 0.86 (0.52–1.40) | 0.92 (0.59–1.43) |
Tumour stage | ||
Local/locoregional | 1 | 1 |
Advanced | 1.56 (1.15–2.10) | 1.71 (1.30–2.25) |
Tumour status | ||
Remission/non-measurable disease | 1 | 1 |
Active malignancy | 1.54 (1.09–2.17) | 1.82 (1.32–2.51) |
Anticancer therapy at COVID-19 diagnosis | ||
No | 1 | 1 |
Yes | 0.81 (0.62–1.06) | 0.72 (0.57–0.92) |
COVID-19 therapy (any) | ||
No | 1 | 1 |
Yes | 0.63 (0.48–0.84) | 0.72 (0.55–0.93) |
Complicated COVID-19 | ||
No | 1 | 1 |
Yes | 6.99 (4.61–10.62) | 4.52 (3.26–6.26) |
COVID-19, coronavirus disease 2019; EU, Europe; UK, United Kingdom; HR, hazard ratio; CI, confidence interval.